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CD73 Antibody (YA3876)(PBS only)

(Synonyms: NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA)

CD73 Antibody (YA3876) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD73.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, FC, ELISA

  • Reactivity :

    Human, Mouse, Rat, Rabbit

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CD73 Antibody (YA3876)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

CD73 Antibody (YA3876) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD73.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat, Rabbit
  • Observed Molecular Weight
    Observed band size: 70 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 63 kDa
Immunogen

Purified recombinant fragment of human NT5E (AA: 30-250) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CD73 (NT5E) is a GPI-anchored extracellular 5'-nucleotidase that regulates immune tolerance, inflammation, and tumor immune escape by converting AMP into the immunosuppressive molecule adenosine. In immunological assays, CD73 serves as a key marker for studying Treg function, the immunosuppressive microenvironment, and tumor immunity.

  • Subcellular Localization

    Cell membrane; Lipid-anchor, GPI-anchor

  • Isoforms & Post-Translational Modification

    CD73 has 2 isomers: P21589-1: 63368 Da (predicted); P21589-2: 57949 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    P21589

  • Gene ID
    4907 [NCBI]
  • Synonyms

    NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA

CD73 Antibody (YA3876)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CD73 Antibody (YA3876)(PBS only) Product Image