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Cat. No.: HY-P86256

CD89 Antibody (YA5948)

Name: CD89 Antibody (YA5948)
Brand: MedChemExpress
SKU: HY-P86256
Availability: PreOrder

(Synonyms: FCAR; CD89; Immunoglobulin alpha Fc receptor ; IgA Fc receptor; CD antigen CD89; )

CD89 Antibody (YA5948) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	ICC	FC 1	IP IP: Immunoprecipitation
Dilution Ratio	1:1000-5000	1:100-300	ICC/IF: 1:100-300	100-300	1:50-100

Description

CD89 Antibody (YA5948) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.

Host Rabbit
Clonality Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CD89 binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production
Subcellular Localization

Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Secreted; Secreted
Expression

Tissue_specificity:Subtypes A.1, A.2, and A.3 are differentially expressed in blood and mucosal myeloid cells. Subtypes A.1, A.2, and A.3 are expressed in monocytes. Subtypes A.1 and A.2 are expressed in alveolar macrophages; however, only one subtype is expressed on the surface of alveolar macrophages.
Isoforms & Post-Translational Modification

P24071 has 11 isomers: P24071-1: 32265 Da (predicted); P24071-2: 29683 Da (predicted); P24071-3: 21694 Da (predicted); P24071-4: 26996 Da (predicted); P24071-5: 25656 Da (predicted); P24071-6: 32629 Da (predicted); P24071-7: 19593 Da (predicted); P24071-8: 23394 Da (predicted); P24071-9: 20354 Da (predicted); P24071-10: 30925 Da (predicted); P24071-11: 28343 Da (predicted).
Subunit

Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2
SwissProt ID

P24071
Gene ID

2204 [NCBI]
Synonyms

FCAR; CD89; Immunoglobulin alpha Fc receptor ; IgA Fc receptor; CD antigen CD89;