CD89 Antibody (YA5948)

Cat. No.: HY-P86256: Data Sheet User Guide for Antibodies
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CD89 Antibody (YA5948) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CD89 Antibody (YA5948) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD89.

Host

Rabbit

Clonality

Monoclonal

Molecular Weight

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P24071

Gene ID

2204 [NCBI]

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-300
ICC	ICC/IF: 1:100-300
FC 1	100-300
IP IP: Immunoprecipitation	1:50-100

Purity	Protein A	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Secreted; Secreted

Expression：
Tissue_specificity:Subtypes A.1, A.2, and A.3 are differentially expressed in blood and mucosal myeloid cells. Subtypes A.1, A.2, and A.3 are expressed in monocytes. Subtypes A.1 and A.2 are expressed in alveolar macrophages; however, only one subtype is expressed on the surface of alveolar macrophages.

Isoforms & Post-Translational Modification：P24071 has 11 isomers: P24071-1: 32265 Da (predicted); P24071-2: 29683 Da (predicted); P24071-3: 21694 Da (predicted); P24071-4: 26996 Da (predicted); P24071-5: 25656 Da (predicted); P24071-6: 32629 Da (predicted); P24071-7: 19593 Da (predicted); P24071-8: 23394 Da (predicted); P24071-9: 20354 Da (predicted); P24071-10: 30925 Da (predicted); P24071-11: 28343 Da (predicted).

Subunit：Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2

Synonyms

FCAR; CD89; Immunoglobulin alpha Fc receptor ; IgA Fc receptor; CD antigen CD89;

Documentation

User Guide for Antibodies (1077 KB)