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CFHR5 Antibody (YA4468)(PBS only)

(Synonyms: FHR5; CFHL5; FHR-5; CFHR5D)

CFHR5 Antibody (YA4468) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CFHR5.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, IHC-P, ICC/IF, FC, ELISA

  • Reactivity :

    Human, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for CFHR5 Antibody (YA4468)(PBS only)
  • CFHR5 Antibody (YA4468)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

CFHR5 Antibody (YA4468) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CFHR5.

  • Host Mouse
  • Species Reactivity
    Human, Mouse
  • Observed Molecular Weight
    Observed band size: 50 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 64.4 kDa
Immunogen

Purified recombinant fragment of human CFHR5 (AA: 344-569) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for CFHR5 Antibody (YA4468)(PBS only)
    Western blot analysis of extracts from HepG2(lane 2(20ug) , K562(lane 3(20ug) and NIH/3T3(lane 4(20ug) using CFHR5 Antibody (HY-P84771) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

  • Function

    CFHR5 is involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH

  • Subcellular Localization

    Secreted

  • Expression


    Tissue_specificity:Expressed by the liver and secreted in plasma

  • Subunit

    Head-to-tail homodimer and heterodimer with CFHR1 or CFHR2. Binds C3b in vitro

  • SwissProt ID

    Q9BXR6

  • Gene ID
    81494 [NCBI]
  • Synonyms

    FHR5; CFHL5; FHR-5; CFHR5D

CFHR5 Antibody (YA4468)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedchemExpress Validation
     Western blot analysis of extracts from HepG2(lane 2(20ug) , K562(lane 3(20ug) and NIH/3T3(lane 4(20ug) using CFHR5 Antibody (HY-P84771) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

  • CFHR5 Antibody (YA4468)(PBS only) Product Image
    1/16
  • Experimental Validation Results for CFHR5 Antibody (YA4468)(PBS only)
  • CFHR5 Antibody (YA4468)(PBS only) Product Image
  • Experimental Validation Results for CFHR5 Antibody (YA4468)(PBS only)
    1/1
    MedchemExpress Validation
     Western blot analysis of extracts from HepG2(lane 2(20ug) , K562(lane 3(20ug) and NIH/3T3(lane 4(20ug) using CFHR5 Antibody (HY-P84771) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
  • Experimental Validation Results for CFHR5 Antibody (YA4468)(PBS only)
  • CFHR5 Antibody (YA4468)(PBS only) Product Image
    MedchemExpress Validation

    Western blot analysis of extracts from HepG2(lane 2(20ug) , K562(lane 3(20ug) and NIH/3T3(lane 4(20ug) using CFHR5 Antibody (HY-P84771) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

  • CFHR5 Antibody (YA4468)(PBS only) Product Image WB