DBI Antibody
(Synonyms: Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, Endozepine, DBI, EP)DBI Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to DBI.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
DBI Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to DBI.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 12 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 10 kDa
Synthetic peptide corresponding to the C-term region of human DBI.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DBI binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor
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Subcellular Localization
Endoplasmic reticulum; Golgi apparatus
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Expression
Tissue_Specificity: Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart. -
Isoforms & Post-Translational Modification
DBI has 6 isoforms, P07108-1: amino acid length is 87, molecular weight is 10044 Da (predicted); P07108-2: amino acid length is 104, molecular weight is 11793 Da (predicted); P07108-3: amino acid length is 88, molecular weight is 10145 Da (predicted); P07108-4: amino acid length is 129, molecular weight is 14367 Da (predicted); P07108-5: amino acid length is 148, molecular weight is 16495 Da (predicted); P07108-6: amino acid length is 123, molecular weight is 13911 Da (predicted).DBI 存在 6 个异构体，P07108-1：氨基酸个数为 87 个，分子量为 10044 Da (预测)；P07108-2：氨基酸个数为 104 个，分子量为 11793 Da (预测)；P07108-3：氨基酸个数为 88 个，分子量为 10145 Da (预测)；P07108-4：氨基酸个数为 129 个，分子量为 14367 Da (预测)；P07108-5：氨基酸个数为 148 个，分子量为 16495 Da (预测)；P07108-6：氨基酸个数为 123 个，分子量为 13911 Da (预测)。
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Subunit
Monomer
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SwissProt ID
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Synonyms
Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, Endozepine, DBI, EP
Documentation
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