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Integrin beta 5 Antibody (YA3108)

(Synonyms: Integrin beta-5)
Customer Review

Based on 1 Customer Validation

Integrin beta 5 Antibody (YA3108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin beta 5.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human, Hamster, Rat

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for Integrin beta 5 Antibody (YA3108)
  • Integrin beta 5 Antibody (YA3108) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

Integrin beta 5 Antibody (YA3108) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin beta 5.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Hamster, Rat
  • Observed Molecular Weight
    Observed band size: 88 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 88 kDa
Species Reactivity Database
Immunogen

Recombinant protein of human Integrin beta 5

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3105476

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for Integrin beta 5 Antibody (YA3108)
    Western blot analysis of extracts from A549 (lane2, 20μg), HT-29 (lane3, 20μg), PANC-1 (lane4, 20μg) and C6 (lane5, 20μg) using Integrin beta 5 Antibody (HY-P83363). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80993, 1/10,000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001,1/10,000) was used for 1 hour at room temperature.

Background

  • Function

    Integrin beta 5 is an Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand; (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for adenovirus type C

  • Subcellular Localization

    Cell membrane; Single-pass type I membrane protein

  • Subunit

    Heterodimer of an alpha and a beta subunit. Beta-5 (ITGB5) associates with alpha-V (ITGAV). Interacts with MYO10 (PubMed:15156152). Interacts with DAB2.

  • SwissProt ID

    P18084

  • Gene ID
    3693 [NCBI]
  • Synonyms

    Integrin beta-5

  • Research Field

    Signal Transduction

Integrin beta 5 Antibody (YA3108) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from A549 (lane2, 20μg), HT-29 (lane3, 20μg), PANC-1 (lane4, 20μg) and C6 (lane5, 20μg) using Integrin beta 5 Antibody (HY-P83363). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80993, 1/10,000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001,1/10,000) was used for 1 hour at room temperature.

  • Integrin beta 5 Antibody (YA3108) Product Image
    1/16
  • Experimental Validation Results for Integrin beta 5 Antibody (YA3108)
  • Integrin beta 5 Antibody (YA3108) Product Image
  • Experimental Validation Results for Integrin beta 5 Antibody (YA3108)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from A549 (lane2, 20μg), HT-29 (lane3, 20μg), PANC-1 (lane4, 20μg) and C6 (lane5, 20μg) using Integrin beta 5 Antibody (HY-P83363). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80993, 1/10,000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001,1/10,000) was used for 1 hour at room temperature.
  • Experimental Validation Results for Integrin beta 5 Antibody (YA3108)
  • Integrin beta 5 Antibody (YA3108) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from A549 (lane2, 20μg), HT-29 (lane3, 20μg), PANC-1 (lane4, 20μg) and C6 (lane5, 20μg) using Integrin beta 5 Antibody (HY-P83363). Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80993, 1/10,000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (HY-P8001,1/10,000) was used for 1 hour at room temperature.

  • Integrin beta 5 Antibody (YA3108) Product Image WB