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MetRS Antibody (YA3196)(PBS only)

(Synonyms: MRS; ILLD; CMT2U; ILFS2; METRS; MTRNS; SPG70)

MetRS Antibody (YA3196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MetRS.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-F, IHC-P, ICC/IF, FC, IP

  • Reactivity :

    Human, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • MetRS Antibody (YA3196)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:1000-1:5000 1:500-1:2000 1:50-1:200 1:20-1:50 1:20-1:50

Product Details

Description

MetRS Antibody (YA3196) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MetRS.

  • Host Rabbit
  • Species Reactivity
    Human, Rat
  • Observed Molecular Weight
    Observed band size: 101 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 101 kDa
Immunogen

A synthetic peptide of human MARS

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MetRS catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus[1][2].

  • Subcellular Localization

    Cytoplasm, cytosol; Nucleus, nucleolus

  • Isoforms & Post-Translational Modification

    P56192 has 2 isomers: P56192-1: 101116 Da (predicted); P56192-2: 61816 Da (predicted).

  • Subunit

    Monomer (PubMed:11714285). Part of a multisubunit complex that groups tRNA ligases for Arg (RARS1), Asp (DARS1), Gln (QARS1), Ile (IARS1), Leu (LARS1), Lys (KARS1), Met (MARS1) the bifunctional ligase for Glu and Pro (EPRS1) and the auxiliary subunits AIMP1/p43, AIMP2/p38 and EEF1E1/p18 (PubMed:19131329, PubMed:19289464, PubMed:26472928, Ref.26). Forms a linear complex that contains MARS1, EEF1E1, EPRS1 and AIMP2 that is at the core of the multisubunit complex (PubMed:26472928)

  • SwissProt ID

    P56192

  • Gene ID
    4141 [NCBI]
  • Synonyms

    MRS; ILLD; CMT2U; ILFS2; METRS; MTRNS; SPG70

  • Research Field

    Signal Transduction

MetRS Antibody (YA3196)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • MetRS Antibody (YA3196)(PBS only) Product Image