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Mouse MHC Class I (H-2Db) Antibody (YA10044)

(Synonyms: RNF82; TIF1; TIF1A; Transcription intermediary factor 1-alpha; TIF1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; Tripartite motif-containing protein 24)

Mouse MHC Class I (H-2Db) Antibody (YA10044) is a Mouse-derived and non-conjugated IgG2a Monoclonal antibody, targeting to Mouse MHC Class I (H-2Db).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    ICC/IF, FC

  • Reactivity :

    Mouse

  • Formulation:

    Supplied in PBS (pH 7.4), containing 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • Mouse MHC Class I (H-2Db) Antibody (YA10044) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:50-200 1:500-2000

Product Details

Description

Mouse MHC Class I (H-2Db) Antibody (YA10044) is a Mouse-derived and non-conjugated IgG2a Monoclonal antibody, targeting to Mouse MHC Class I (H-2Db).

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Mouse
Immunogen

Purified recombinant protein of Mouse H-2Db.

Sensitivity

Endogenous

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH 7.4), containing 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Mouse MHC Class I is involved in the presentation of foreign antigens to the immune system

  • Subcellular Localization

    Membrane

  • Isoforms & Post-Translational Modification

    Mouse MHC Class I has an amino acid length of 362, molecular weight is 40836 Da.
    Polyubiquitinated in case of infection by murid herpesvirus 4, by the viral E3 ligase K3 (mK3). This modification causes the protein to be targeted for rapid degradation by the endoplasmic reticulum-associated degradation (ERAD) system. Ubiquitination occurs on lysine, as well as serine and threonine residues present in the cytoplasmic tail. Serine and threonine residues are subject to ubiquitination via ester bonds instead of the usual isopeptide linkage.

  • Subunit

    Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).

  • SwissProt ID

    P01899

  • Gene ID
    14964 [NCBI]
  • Synonyms

    RNF82; TIF1; TIF1A; Transcription intermediary factor 1-alpha; TIF1-alpha; E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; Tripartite motif-containing protein 24

Mouse MHC Class I (H-2Db) Antibody (YA10044) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Mouse MHC Class I (H-2Db) Antibody (YA10044) Product Image