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NDUFAB1 Antibody (YA6676)

(Synonyms: ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 8kDa antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 antibody; NADH ubiquinone oxidoreductase 9.6 kDa subunit antibody; NADH ubiquinone oxidoreductase SDAP subunit antibody; NADH-ubiquinone oxidoreductase 9.6 kDa subunit antibody; NDUFAB 1 antibody; ndufab1 antibody; SDAP antibody; )
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NDUFAB1 Antibody (YA6676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NDUFAB1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500 1:200-1:1000 1:500-1:1000

Product Details

Description

NDUFAB1 Antibody (YA6676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NDUFAB1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 16 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 17 kDa
Immunogen

Recombinant protein within human NDUFAB1 aa 57-156/156.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    NDUFAB1 is a Carrier of the growing fatty acid chain in fatty acid biosynthesis. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. Accessory protein, of the core iron-sulfur cluster (ISC) assembly complex, that regulates, in association with LYRM4, the stability and the cysteine desulfurase activity of NFS1 and participates in the [2Fe-2S] clusters assembly on the scaffolding protein ISCU. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5[1][2].

  • Subcellular Localization

    Mitochondrion

  • Isoforms & Post-Translational Modification

    O14561: 156 amino acids, molecular weight 17417 Da.

  • Subunit

    Mammalian complex I is composed of 45 different subunits (PubMed:12611891)

  • SwissProt ID

    O14561

  • Gene ID
    4706 [NCBI]
  • Synonyms

    ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; ACP antibody; ACPM_HUMAN antibody; Acyl carrier protein antibody; Acyl carrier protein mitochondrial antibody; CI SDAP antibody; CI-SDAP antibody; FASN 2A antibody; FASN2A antibody; MGC65095 antibody; Mitochondrial acyl carrier protein antibody; mitochondrial antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 8kDa antibody; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 antibody; NADH ubiquinone oxidoreductase 9.6 kDa subunit antibody; NADH ubiquinone oxidoreductase SDAP subunit antibody; NADH-ubiquinone oxidoreductase 9.6 kDa subunit antibody; NDUFAB 1 antibody; ndufab1 antibody; SDAP antibody;

NDUFAB1 Antibody (YA6676) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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