NRF-1 Antibody (YA260)(PBS only)

Cat. No.: HY-P80769A: Ficha de datos User Guide for Antibodies
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NRF-1 Antibody (YA260) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRF-1.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

NRF-1 Antibody (YA260) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NRF-1.

Host

Rabbit

Peso molecular

Predicted band size: 54 kDa;

Observed band size: 68 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q16656

Gene ID

4899 [NCBI]

Immunogen

Synthetic peptide corresponding to Human NRF1.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Pureza	affinity purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:It is widely expressed, with the strongest expression in skeletal muscle.

Isoforms & Post-Translational Modification：Q16656 has 4 isomers: Q16656-1: 53541 Da (predicted); Q16656-2: 46157 Da (predicted); Q16656-3: 36051 Da (predicted); Q16656-4: 55674 Da (predicted).
Phosphorylation enhances DNA binding

Subunit：Homodimer. Binds DNA as a dimer. Interacts with PPRC1

Research Field

Epigenetics and Nuclear Signaling

Synonyms

alpha pal; alpha palindromic binding protein; Alpha palindromic-binding protein; Alpha-pal; locus control region factor 1; NFE2 related factor 1; NRF-1; Nrf1; NRF1_HUMAN; Nuclear respiratory factor 1; transcription factor 11.

Documentación

User Guide for Antibodies (1077 KB)