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Cat. No.: HY-P86280

PACSIN3 Antibody (YA5972)

Name: PACSIN3 Antibody (YA5972)
Brand: MedChemExpress
SKU: HY-P86280
Availability: PreOrder

(Synonyms: PACSIN3; Protein kinase C and casein kinase substrate in neurons protein 3 ; SH3 domain-containing protein 6511; )

PACSIN3 Antibody (YA5972) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PACSIN3.

For research use only. We do not sell to patients.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	ICC	FC 1	IP IP: Immunoprecipitation
Dilution Ratio	1:1000-5000	1:100-300	ICC/IF: 1:100-300	100-300	1:50-100

Description

PACSIN3 Antibody (YA5972) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PACSIN3.

Host Rabbit
Clonality Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 47 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Purification

Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

PACSIN3 plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity
Subcellular Localization

Cytoplasm; Cell membrane; Peripheral membrane protein; Cytoplasmic side
Expression

Tissue_specificity:This gene is widely expressed in various tissues, with the highest concentrations in the heart and skeletal muscle, moderate concentrations in the placenta, liver, and pancreas, and extremely low concentrations in the brain, lungs, and kidneys.
Subunit

Homodimer. May form heterooligomers with other PACSINs.
SwissProt ID

Q9UKS6
Gene ID

29763 [NCBI]
Synonyms

PACSIN3; Protein kinase C and casein kinase substrate in neurons protein 3 ; SH3 domain-containing protein 6511;