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  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. Pinch-1 Antibody (YA4043)(PBS only)

Pinch-1 Antibody (YA4043)(PBS only)

製品番号: HY-P84346A
User Guide for Antibodies Technical Support

Pinch-1 Antibody (YA4043) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Pinch-1.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

Pinch-1 Antibody (YA4043) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Pinch-1.
Host

Mouse
分子量
Predicted band size: 37 kDa;
Observed band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Purified recombinant fragment of human PINCH aa 87-249.
Application &
Dilution Ratio
Application Dilution Ratio
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:200-1:1000
FC
FC: Flow Cytometry
1:200-1:400
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
純度 affinity purified. Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration
Subcellular Localization：Cell junction, focal adhesion; Cell membrane; Peripheral membrane protein; Cytoplasmic side
Expression：
Tissue_specificity:It is expressed in most tissues except the brain.
Subunit：Component of the heterotrimeric IPP (ILK-PINCH-PARVIN) complex composed of ILK, LIMS1/PINCH and PARVA; the complex binds to F-actin via the C-terminal tail of LIMS1 and the N-terminal region of PARVA, promoting F-actin filament bundling (PubMed:11331308, PubMed:12432066, PubMed:30367047).
Synonyms
PINCH; PINCH1; PINCH-1; LIMS1
ドキュメンテーション
User Guide for Antibodies (1077 KB)

Pinch-1 Antibody (YA4043)(PBS only) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Pinch-1 Antibody (YA4043)(PBS only)
製品番号:
HY-P84346A
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