RIOK2 Antibody (YA8047)(PBS only)

Cat. No.: HY-P88363A: Data Sheet User Guide for Antibodies
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RIOK2 Antibody (YA8047) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RIOK2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

RIOK2 Antibody (YA8047) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RIOK2.

Host

Mouse

Molecular Weight

Predicted band size: 63.1 kDa

Species Reactivity

Human

SwissProt ID

Q9BVS4

Immunogen

Human recombinant protein fragment corresponding to amino acids 277-552 of human RIOK2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA (PubMed:19564402). Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function (PubMed:21880710)

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：Q9BVS4 has two isomers: Q9BVS4-1: 63283 Da (predicted); Q9BVS4-2: 54508 Da (predicted).
Autophosphorylated (in vitro) (PubMed:19564402, PubMed:21880710)

Subunit：Associated with late 40S pre-ribosomal particles (PubMed:16037817, PubMed:21081503)

Synonyms

RIO2

Documentation

User Guide for Antibodies (1077 KB)