RIOK2
RIOK2 operates in cytoplasmic 40S ribosomal-subunit maturation and, relative to RIOK1, is distinguished by its association with pre-40S intermediates and its interplay with the endonuclease NOB1 during the final cleavage of 18S rRNA. Like the other RIO-family atypical kinases, RIOK2 adopts a divergent catalytic fold and is considered essential for viability of human cells. It is frequently overexpressed in proliferating and transformed cells, and its depletion stalls 18S processing and reduces translational capacity. Recombinant RIOK2 is used to dissect late ribosome-biogenesis steps, to assay atypical kinase activity and to explore RIOK2 as a proliferation-linked target.
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RIOK2 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
