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Stra8 Antibody (YA6873)

(Synonyms: Stimulated by retinoic acid 8 antibody; STRA 8 antibody)
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Based on 1 Customer Validation

Stra8 Antibody (YA6873) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Stra8.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, FC

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for Stra8 Antibody (YA6873)
  • Stra8 Antibody (YA6873) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:1000 1:250 1:1000

Product Details

Description

Stra8 Antibody (YA6873) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Stra8.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 35 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size：37 kDa
Immunogen

Recombinant protein within human Stra8 aa 1-330 / 330.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3719284

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for Stra8 Antibody (YA6873)
    Western blot analysis of extracts from LNCap (lane 1(20μg)) 、Hela (lane 2(20μg)) 、HT1080 (lane 3(20μg)) and Jurkat (lane 4(20μg)) using Stra8 Antibody (HY-P87185) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

  • Function

    Stra8 is a Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis

  • Subcellular Localization

    Cytoplasm,Nucleus

  • Expression


    Tissue_Specificity: Expressed specifically in testis and fetal ovaries

  • Isoforms & Post-Translational Modification

    Q7Z7C7: 330 amino acids, molecular weight 36908 Da.

  • Subunit

    Interacts with XPO1

  • SwissProt ID

    Q7Z7C7

  • Synonyms

    Stimulated by retinoic acid 8 antibody; STRA 8 antibody

Stra8 Antibody (YA6873) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from LNCap (lane 1(20μg)) 、Hela (lane 2(20μg)) 、HT1080 (lane 3(20μg)) and Jurkat (lane 4(20μg)) using Stra8 Antibody (HY-P87185) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • Stra8 Antibody (YA6873) Product Image
    1/16
  • Experimental Validation Results for Stra8 Antibody (YA6873)
  • Stra8 Antibody (YA6873) Product Image
  • Experimental Validation Results for Stra8 Antibody (YA6873)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from LNCap (lane 1(20μg)) 、Hela (lane 2(20μg)) 、HT1080 (lane 3(20μg)) and Jurkat (lane 4(20μg)) using Stra8 Antibody (HY-P87185) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.
  • Experimental Validation Results for Stra8 Antibody (YA6873)
  • Stra8 Antibody (YA6873) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from LNCap (lane 1(20μg)) 、Hela (lane 2(20μg)) 、HT1080 (lane 3(20μg)) and Jurkat (lane 4(20μg)) using Stra8 Antibody (HY-P87185) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • Stra8 Antibody (YA6873) Product Image WB