CCT2 Antibody (YA5077)
(Synonyms: CCT2; 99D8.1; CCTB; T-complex protein 1 subunit beta; TCP-1-beta; CCT-beta)Based on 1 Customer Validation
CCT2 Antibody (YA5077) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to CCT2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, IP, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-200 | 1:50-200 | 1:50-200 | 1:50-200 | 1:20-50 | 1:50-100 |
Product Details
CCT2 Antibody (YA5077) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to CCT2.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 59 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 57 kDa
A synthesized peptide derived from human TCP 1 beta. The exact sequence is proprietary to MCE.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CCT2 component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia[1][2][3][4][5].
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
P78371 has 2 isomers: P78371-1: 57488 Da (predicted); P78371-2: 52718 Da (predicted).
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Subunit
Component of the chaperonin-containing T-complex (TRiC), a hexadecamer composed of two identical back-to-back stacked rings enclosing a protein folding chamber (PubMed:20080638, PubMed:25467444, PubMed:36493755, PubMed:35449234, PubMed:37193829).
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SwissProt ID
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Synonyms
CCT2; 99D8.1; CCTB; T-complex protein 1 subunit beta; TCP-1-beta; CCT-beta
Documentation