TNFRSF25 Antibody (YA4413)(PBS only)

Cat. No.: HY-P84716A: Data Sheet User Guide for Antibodies
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TNFRSF25 Antibody (YA4413) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TNFRSF25.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

TNFRSF25 Antibody (YA4413) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TNFRSF25.

Host

Mouse

Molecular Weight

Predicted band size: 45.4 kDa

Species Reactivity

Human

SwissProt ID

Q93038

Gene ID

8718 [NCBI]

Immunogen

Purified recombinant fragment of human TNFRSF25 (AA: extra(25-199)) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Cell membrane; Single-pass type I membrane protein; Secreted; Secreted; Secreted; Secreted; Secreted; Secreted; Secreted; Secreted

Expression：
Tissue_specificity:Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate

Isoforms & Post-Translational Modification：Q93038 has 12 isomers: Q93038-1: 45385 Da (predicted); Q93038-2: 45456 Da (predicted); Q93038-3: 23198 Da (predicted); Q93038-4: 27004 Da (predicted); Q93038-5: 19432 Da (predicted); Q93038-6: 14439 Da (predicted); Q93038-7: 13349 Da (predicted); Q93038-8: 25373 Da (predicted); Q93038-9: 40391 Da (predicted); Q93038-10: 41193 Da (predicted); Q93038-11: 45928 Da (predicted); Q93038-12: 29111 Da (predicted).
(Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1;Glycosylated

Subunit：Homodimer. Interacts strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. Interacts with BAG4

Synonyms

DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; GEF720; WSL-LR; PLEKHG5; TNFRSF12

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/kns-62-cell.html