UCHL5 Antibody (YA2339)(PBS only)

Cat. No.: HY-P82594A: Data Sheet User Guide for Antibodies
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UCHL5 Antibody (YA2339) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to UCHL5.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

UCHL5 Antibody (YA2339) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to UCHL5.

Host

Rabbit

Molecular Weight

Predicted band size: 38 kDa;

Observed band size: 38 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y5K5

Gene ID

51377 [NCBI]

Immunogen

A synthetic peptide of human UCH37

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1

Subcellular Localization：Cytoplasm; Nucleus

Isoforms & Post-Translational Modification：Q9Y5K5 has 4 isomers: Q9Y5K5-1: 37607 Da (predicted); Q9Y5K5-2: 36079 Da (predicted); Q9Y5K5-3: 37478 Da (predicted); Q9Y5K5-4: 37353 Da (predicted).

Subunit：Component of the 19S (PA700) regulatory complex of the 26S proteasome. Interacts with ADRM1 and NFRKB; in vitro ADRM1 and NFRKB compete for interaction with UCHL5. Component of the INO80 complex; specifically part of a complex module associated with N-terminus of INO80

Research Field

Cell Biology

Synonyms

UCH37; CGI-70; INO80R; UCH-L5

Documentation

User Guide for Antibodies (1077 KB)