ZHX2 Antibody (YA1746)(PBS only)

Cat. No.: HY-P82001A: Data Sheet User Guide for Antibodies
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ZHX2 Antibody (YA1746) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ZHX2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ZHX2 Antibody (YA1746) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ZHX2.

Host

Rabbit

Molecular Weight

Predicted band size: 92 kDa;

Observed band size: 110 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y6X8

Gene ID

22882 [NCBI]

Immunogen

Recombinant protein of human ZHX2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:200
FC FC: Flow Cytometry	1:50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity)

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Ubiquitously expressed. Expressed in podocytes

Subunit：Homodimer (via homeobox domain) (PubMed:12741956, PubMed:14659886). Heterodimer with ZHX1 (via homeobox domain 1) (PubMed:12741956). Heterodimer with ZHX3 (via homeobox domain 1) (PubMed:12741956, PubMed:14659886). Heterodimerization with ZHX1 is not necessary for repressor activity (PubMed:12741956). Interacts (via homeobox domain) with NFYA (via N-terminus) (PubMed:12741956). Interacts with EFNB1 intracellular domain peptide; the interaction enhances ZHX2 transcriptional repression activity (By similarity)

Research Field

Epigenetics and Nuclear Signaling

Synonyms

AFP regulator 1; Zinc finger and homeodomain protein 2

Documentation

User Guide for Antibodies (1077 KB)