Antiparasitic agent-21
Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC50 of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability.
For research use only. We do not sell to patients.
- CAS No.: 3027004-49-2
- Formula: C18H22N2O3
- Molecular Weight:314.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SH-SY5Y | CC50 |
>20 μM
Compound: 28
|
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by celltiter glow assay
Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability incubated for 72 hrs by celltiter glow assay
|
[PMID: 38229759] |
Chemical Information
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CAS No. 3027004-49-2
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Molecular Weight 314.38
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Formula C18H22N2O3
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SMILES
O=C(O)C1=NC=C(OC)C=C1NCC2=CC=C(C(C)(C)C)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)