Jingsongling
Jingsongling is a Xylazine analog and anesthetic agent. Jingsongling causes bradycardia and hypertension by mediating α2-adrenoceptors. Jingsongling inhibits canine gastric motility through mediation of α1 and α2 adrenergic receptors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 25332-05-2
- Formel: C11H14N2S
- Molecular Weight:206.31
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
|
α1-adrenergic receptor |
α2-adrenergic receptor |
Chemical Information
-
CAS. Nr. 25332-05-2
-
Molecular Weight 206.31
-
Formel C11H14N2S
-
SMILES
CC1=C(NC2=NCCS2)C(C)=CC=C1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
-
Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.
Reinheit & Dokumentation
Verweise
[1]. Hsu WH, et al. The effects of jingsongling, a xylazine analog, on mean arterial blood pressure and heart rate in dogs--influences of yohimbine, tolazoline, prazosin, and atropine. J Vet Pharmacol Ther. 1989 Sep;12(3):283-8. [Content Brief]
[2]. Lin DeGui L D G, et al. Studies on effect of Jingsongling on canine gastric peristalsis[J]. 2001.
[3]. Guo LQ, et al. [Studies on biotransformation of jing song ling, a new anesthetic]. Yao Xue Xue Bao. 1990;25(2):95-100. Chinese. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Jingsongling Related Classifications
HY-118390 Related Classifications
Powered by Bioz