ATG12-ATG3 inhibitor 1

Cat. No.: HY-156966 Purity: 98.19%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

ATG12-ATG3 inhibitor 1 화학구조

CAS No. : 333351-38-5

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

ATG12-ATG3 inhibitor 1 (compound 189) is a potent inhibitor of autophage^[1].

분자량

327.40

화학식

C₁₈H₁₇NO₃S

CAS No.

333351-38-5

Appearance

Solid

Color

Light yellow to khaki

SMILES

O=S(NC1=CC=C(C2=C1C=CC=C2)O)(C3=CC=C(C)C=C3C)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 250 mg/mL (763.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0544 mL	15.2718 mL	30.5437 mL
5 mM	0.6109 mL	3.0544 mL	6.1087 mL
10 mM	0.3054 mL	1.5272 mL	3.0544 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.19%

Select Batch:

Data Sheet (273 KB) SDS (251 KB)

COA (256 KB) HNMR (257 KB) LCMS (98 KB)

Handling Instructions (2659 KB)

References

[1]. Gal Chaim Nuta, et al. Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction. Autophagy. 2023 Aug;19(8):2372-2385. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0544 mL	15.2718 mL	30.5437 mL	76.3592 mL
	5 mM	0.6109 mL	3.0544 mL	6.1087 mL	15.2718 mL
	10 mM	0.3054 mL	1.5272 mL	3.0544 mL	7.6359 mL
	15 mM	0.2036 mL	1.0181 mL	2.0362 mL	5.0906 mL
	20 mM	0.1527 mL	0.7636 mL	1.5272 mL	3.8180 mL
	25 mM	0.1222 mL	0.6109 mL	1.2217 mL	3.0544 mL
	30 mM	0.1018 mL	0.5091 mL	1.0181 mL	2.5453 mL
	40 mM	0.0764 mL	0.3818 mL	0.7636 mL	1.9090 mL
	50 mM	0.0611 mL	0.3054 mL	0.6109 mL	1.5272 mL
	60 mM	0.0509 mL	0.2545 mL	0.5091 mL	1.2727 mL
	80 mM	0.0382 mL	0.1909 mL	0.3818 mL	0.9545 mL
	100 mM	0.0305 mL	0.1527 mL	0.3054 mL	0.7636 mL