1. Membrane Transporter/Ion Channel
  2. ATP Synthase
  3. ATP synthase inhibitor 1

ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels.

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ATP synthase inhibitor 1 Chemical Structure

ATP synthase inhibitor 1 Chemical Structure

CAS No. : 1023043-30-2

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5 mg USD 160 In-stock
10 mg USD 260 In-stock
25 mg USD 520 In-stock
50 mg USD 830 In-stock
100 mg USD 1350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].

IC50 & Target

F1/FO-ATP synthase[1]

In Vitro

ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

411.93

Formula

C17H18ClN3O3S2

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1NCN(C2=CC=CC=C2)C31CCN(S(=O)(C4=CC=C(Cl)S4)=O)CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4276 mL 12.1380 mL 24.2760 mL
5 mM 0.4855 mL 2.4276 mL 4.8552 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4276 mL 12.1380 mL 24.2760 mL 60.6899 mL
5 mM 0.4855 mL 2.4276 mL 4.8552 mL 12.1380 mL
10 mM 0.2428 mL 1.2138 mL 2.4276 mL 6.0690 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ATP synthase inhibitor 1
Cat. No.:
HY-112715
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