2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. BCR-ABL-IN-4

BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11).

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BCR-ABL-IN-4

BCR-ABL-IN-4 Estructura química

No. CAS : 2669790-59-2

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BCR-ABL-IN-4 Related Antibodies

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Descripciòn

BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1].

Peso molecular

555.96

Fòrmula

C27H24ClF2N5O4
No. CAS
SMILES

ClC(F)(F)OC(C=C1)=CC=C1NC(C2=CC(C3=CN=C(CN(C4CC4)C5=O)C5=C3)=C(N6C[C@@H](CC6)O)N=C2)=O
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BCR-ABL-IN-4 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BCR-ABL-IN-42669790-59-2Bcr-AblBCR-ABL inhibitoranticancer effectsInhibitorinhibitorinhibit

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Nombre del producto:
BCR-ABL-IN-4
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HY-142922
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