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BIBX 1382 dihydrochloride

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Based on 4 publication(s) in Google Scholar

BIBX 1382 dihydrochloride is an ErbB kinase inhibitor with significant antiviral activity. BIBX 1382 affects the ability of viruses to enter host cells by inhibiting members of the ErbB kinase family. It can be used to study the interaction mechanism between virus and host and the broad spectrum intervention of highly pathogenic viruses.

For research use only. We do not sell to patients.

  • CAS No.: 1216920-18-1
  • Formula: C18H21Cl3FN7
  • Molecular Weight:460.76
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • BIBX 1382 dihydrochloride Chemical Structure
    BIBX 1382 dihydrochloride Chemical Structure
  • Experimental Validation Results for BIBX 1382 dihydrochloride
CAS No.: 1216920-18-1
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  • BIBX 1382 dihydrochloride Chemical Structure
    BIBX 1382 dihydrochloride Chemical Structure
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    BIBX 1382 dihydrochloride purchased from MedChemExpress. Usage Cited in: Neuroscience. 2015 Sep 24:304:109-21. [Abstract]

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     GluN2B Y1472 phosphorylation in whole-cell lysate is increased after 5 and 10 min of EGF treatment in cultured neurons which could be blocked by BIBX-1382. EGFR activation increases SFK activity and phosphorylation of GluN2B Y1472. (A) Representative Western blot result of whole lysate samples from hippocampal slices treated with 50 ng/mL EGF incubation for 10 min. (B) Western blot of EGFR-treated DIV14 cultured hippocampal neurons with minimum glia composition shows increased phosphorylation of

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