Veratryl alcohol
Based on 1 publication(s) in Google Scholar
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy.
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- Pureté : 99.98%
- CAS No.: 93-03-8
- Formule: C9H12O3
- Masse moléculaire:168.19
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Veratryl alcohol
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Activité biologique
Description
In Vitro
Veratryl alcohol (512-1024 µg/mL, 24-48 h) inhibits the expression of quorum sensing-related genes such as lasI, lasR, rhlI, rhlR, pqsA and pqsR, reduces the expression of virulence factors such as elastase, protease, pyocyanin and rhamnolipid, interfers with the formation of biofilm, and exhibits inhibitory activity against P. aeruginosa[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:P. aeruginosa infected fruit flies and C. elegans models[4]
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Dosage:512-1024 µg/mL
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Administration:placed on the medium for infection for 5-10 days
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Result:Prolonged the survival rate.
Chemical Information
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CAS No. 93-03-8
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Appearance <22°C Solid, >22°C Liquid
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Masse moléculaire 168.19
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Formule C9H12O3
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Color Colorless to light yellow
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SMILES
OCC1=CC=C(OC)C(OC)=C1
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Synonyms
3,4-Dimethoxybenzyl alcohol
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Structure Classification
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Initial Source
a secondary metabolite of some lignin degrading fungi
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvant et solubilité
In Vitro:
Ethanol : 100 mg/mL (594.56 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Leisola MS, et al. Enzymatic determination of veratryl alcohol. Anal Biochem. 1986 May 15;155(1):108-11. [Content Brief]
[2]. Arias ME, et al. Kraft pulp biobleaching and mediated oxidation of a nonphenolic substrate by laccase from Streptomyces cyaneus CECT 3335. Appl Environ Microbiol. 2003 Apr;69(4):1953-8. [Content Brief]
[3]. Koduri RS, et al., Oxidation of guaiacol by lignin peroxidase. Role of veratryl alcohol. J Biol Chem. 1995 Sep 22;270(38):22254-8. [Content Brief]
[4]. Fu S, et al., Veratryl Alcohol Attenuates the Virulence and Pathogenicity of Pseudomonas aeruginosa Mainly via Targeting las Quorum-Sensing System. Microorganisms. 2024 May 14;12(5):985. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 5.9456 mL | 29.7279 mL | 59.4559 mL | 148.6396 mL |
| 5 mM | 1.1891 mL | 5.9456 mL | 11.8912 mL | 29.7279 mL | |
| 10 mM | 0.5946 mL | 2.9728 mL | 5.9456 mL | 14.8640 mL | |
| 15 mM | 0.3964 mL | 1.9819 mL | 3.9637 mL | 9.9093 mL | |
| 20 mM | 0.2973 mL | 1.4864 mL | 2.9728 mL | 7.4320 mL | |
| 25 mM | 0.2378 mL | 1.1891 mL | 2.3782 mL | 5.9456 mL | |
| 30 mM | 0.1982 mL | 0.9909 mL | 1.9819 mL | 4.9547 mL | |
| 40 mM | 0.1486 mL | 0.7432 mL | 1.4864 mL | 3.7160 mL | |
| 50 mM | 0.1189 mL | 0.5946 mL | 1.1891 mL | 2.9728 mL | |
| 60 mM | 0.0991 mL | 0.4955 mL | 0.9909 mL | 2.4773 mL | |
| 80 mM | 0.0743 mL | 0.3716 mL | 0.7432 mL | 1.8580 mL | |
| 100 mM | 0.0595 mL | 0.2973 mL | 0.5946 mL | 1.4864 mL |
Veratryl alcohol Related Classifications
HY-107858 Related Classifications
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