BACE1-IN-8
BACE1-IN-8 (compound 70b) is a potent BACE1 (β-site APP cleaving enzyme 1) inhibitor, with an IC50 of 3.9 µM.
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- Formule: C29H45N5O7
- Masse moléculaire:575.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
IC50: 3.9 µM (rBACE1)[1]
Chemical Information
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Masse moléculaire 575.70
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Formule C29H45N5O7
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SMILES
CCC[C@@H]1NC([C@@H](NC([C@@H](N)CCC(O)=O)=O)C(OC/C=C\C[C@@H]([C@H](O)CNC2=CC=C(C)C=C2)NC1=O)(C)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)