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Cat. No.: HY-168173

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EGFR-IN-130

EGFR-IN-130 (compound 14b) is an EGFR inhibitor and apoptosis inducer. EGFR-IN-130 triggers death of HeLa cancer cells via apoptosis induction..

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Formule: C₂₇H₂₅N₃O₆S
Masse moléculaire:519.57

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

EGFR-IN-130 Chemical Structure

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Activité biologique

Description

EGFR-IN-130 (compound 14b) is an EGFR inhibitor and apoptosis inducer. EGFR-IN-130 triggers death of HeLa cancer cells via apoptosis induction.^[1].

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Chemical Information

Masse moléculaire 519.57
Formule C₂₇H₂₅N₃O₆S
SMILES

OC1=C(CN(C2=CC(C(OC)=O)=C(O)C=C2)C3=NC(/C(S3)=C/C4=CC=C(N(C)C)C=C4)=O)C=C(O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Othman SA, et al. Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids. Bioorg Chem. 2024 Dec;153:107884. [Content Brief]

Calculators

Calculateur de molarité

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Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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EGFR-IN-130

Voir tous les produits spécifiques à Isoform EGFR

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

EGFR-IN-130 Related Classifications

HY-168173 Related Classifications

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