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Cat. No.: HY-121415

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Herkinorin

Name: Herkinorin
Brand: MedChemExpress
SKU: HY-121415
Price: 250.00 USD
Availability: InStock
Rating: 5 (2 reviews)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Herkinorin is a potent and selective agonist of µ opioid receptor with a K_i of 45 nM Herkinorin is widely used for pain research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 862073-77-6
Formule: C₂₈H₃₀O₈
Masse moléculaire:494.53

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Herkinorin Chemical Structure

CAS No.: 862073-77-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Publications (2)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Herkinorin is a potent and selective agonist of µ opioid receptor with a K_i of 45 nM Herkinorin is widely used for pain research^[1].

Voir tous les produits spécifiques à Isoform Opioid Receptor :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	1320 nM Compound: 1c	Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay	[PMID: 18380425]
CHO	EC₅₀	1320 nM Compound: 13	Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor kappa1 expressed in CHO cells Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor kappa1 expressed in CHO cells	[PMID: 16033256]
CHO	EC₅₀	500 nM Compound: 1c	Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay	[PMID: 18380425]
CHO	EC₅₀	500 nM Compound: 13	Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor mu1 expressed in CHO cells Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor mu1 expressed in CHO cells	[PMID: 16033256]

Chemical Information

CAS No. 862073-77-6
Masse moléculaire 494.53
Formule C₂₈H₃₀O₈
SMILES

O=C([C@H](C[C@H](OC(C1=CC=CC=C1)=O)C([C@@]23[H])=O)[C@]2(C)CC[C@@]([C@]3(C)C[C@@H](C4=COC=C4)O5)([H])C5=O)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Journal Impact Factor

Int Immunopharmacol

Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB. [Abstract]

2025 May 16:155:114588. PMID: 40209309
Neurochem Res

Herkinorin Exerted Neuroprotective Effects After Spinal Cord Injury by Suppression of NF-κB Pathway Activation. [Abstract]

2026 Jun 1;51(3):180. PMID: 42219409

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lamb K, et al. Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Herkinorin

2 Cited Publications

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Activité biologique
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Chemical Information
Publications (2)
Pureté et documentation
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Herkinorin

Publications Citing Use of MedChemExpress (MCE) Herkinorin

Voir tous les produits spécifiques à Isoform Opioid Receptor

Activité biologique

Chemical Information

Publications (2)

Pureté et documentation

Références

Calculators

Help & FAQs

Herkinorin Related Classifications

HY-121415 Related Classifications

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