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Cat. No.: HY-N8280

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IKD-8344

IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties. It is cytotoxic to L5178Y murine leukemia cells (IC₅₀=0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC=6.25 μg/mL) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.

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CAS No.: 129046-69-1
Formule: C₄₈H₇₆O₁₂
Masse moléculaire:845.11

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

IKD-8344 Chemical Structure

CAS No.: 129046-69-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

CAS No. 129046-69-1
Masse moléculaire 845.11
Formule C₄₈H₇₆O₁₂
SMILES

C[C@@H]([C@@](CC1)([H])O[C@@H]1C)[C@@](OC([C@H]([C@@]2([H])O[C@@H](CC([C@@H]([C@](CC3)([H])O[C@]3([H])C4)C)=O)CC2)C)=O)([H])C[C@@]5([H])O[C@]([C@H](C(C[C@@H]6O[C@@]([C@@H](C(O[C@@]4([H])[C@H]([C@@](CC7)([H])O[C@@H]7C)C)=O)C)([H])CC6)=O)C)([H])CC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Minami, et al. Structure of a novel macrodiolide antibiotic IKD-8344. Tetrahedron Lett. 33(48), 7373-7376 (1992).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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