Cabralealactone
Cabralealactone (Dipterocarpon) is a Alkaloids product that can be isolated from the root barks of Dictamnus dasycarpus..
For research use only. We do not sell to patients.
- CAS No.: 19865-87-3
- Formula: C27H42O3
- Molecular Weight:414.62
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | IC50 |
>40 μM
Compound: 13
|
Cytotoxicity against human 786-O cells after 72 hrs by MTT assay
Cytotoxicity against human 786-O cells after 72 hrs by MTT assay
|
[PMID: 30106297] |
| A549 | IC50 |
>40 μM
Compound: 13
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 30106297] |
| A549 | IC50 |
>50 μM
Compound: 18
|
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 24547740] |
| COLO 205 | IC50 |
>100 μM
Compound: 14
|
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
Cytotoxicity against human COLON205 cells after 48 hrs by MTT assay
|
[PMID: 17346076] |
| HeLa | IC50 |
>40 μM
Compound: 13
|
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
|
[PMID: 30106297] |
| HepG2 | IC50 |
>40 μM
Compound: 13
|
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
|
[PMID: 30106297] |
| HepG2 | IC50 |
>50 μM
Compound: 18
|
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 24547740] |
| K562 | IC50 |
>100 μM
Compound: 14
|
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
|
[PMID: 17346076] |
| K562/Adr | IC50 |
>100 μM
Compound: 14
|
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells after 48 hrs by MTT assay
|
[PMID: 17346076] |
| K562/Adr | IC50 |
>100 μM
Compound: 14
|
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
Cytotoxicity against human doxorubicin-resistant K562/Adr cells in presence of 1 uM doxorubicin after 48 hrs by MTT assay
|
[PMID: 17346076] |
| KB | IC50 |
63.5 μM
Compound: 14
|
Cytotoxicity against human KB cells after 48 hrs by MTT assay
Cytotoxicity against human KB cells after 48 hrs by MTT assay
|
[PMID: 17346076] |
| MCF7 | IC50 |
>50 μM
Compound: 18
|
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 24547740] |
| MCF7 | IC50 |
97.9 μM
Compound: 14
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 17346076] |
| RAW264.7 | IC50 |
>100 μM
Compound: 18
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay
|
[PMID: 24547740] |
Chemical Information
-
CAS No. 19865-87-3
-
Molecular Weight 414.62
-
Formula C27H42O3
-
SMILES
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@]4(OC(CC4)=O)C)C)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC1)C
-
Synonyms
Dipterocarpon
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)