155521-45-2

Alisol F Chemical Structure
155521-45-2

Chemical Structure

Alisol F

  • CAS No.: 155521-45-2
  • Formula:C30H48O5
  • Molecular Weight:488.70

IUPAC Name: (2aR,6aS,6bS,7S,9R,11S,12aS,13aR,13bS)-11-((R)-1,2-dihydroxy-2-methylpropyl)-7-hydroxy-3,3,6a,9,13a,13b-hexamethyl-1,2a,3,5,6,6a,6b,7,8,9,10,11,12a,13,13a,13b-hexadecahydronaphtho[2',1':4,5]indeno[2,1-b]pyran-4(2H)-one

InChIKey: YNKJSQIXVXWFBK-SLGDLKFASA-N

SMILES: C[C@]1(C(C[C@@H]2O)=C([C@@H]3C)[C@](O[C@@]([C@@H](O)C(C)(O)C)([H])C3)([H])C1)[C@]([C@]2([H])[C@]4(CCC5=O)C)(CC[C@@]4([H])C5(C)C)C

Biological Activity: Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS (HY-D1056)-induced phosphorylation of ERK, JNK, p38, STAT3 and NF-κB (p65), suppresses the production of NO, IL-6, TNF-α and IL-1β, and also downregulates the levels of iNOS and COX-2. Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage[1][2].

Cat. No. Product Name Purity Description Pricing
HY-N0854 		Alisol F 99.89% Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS (HY-D1056)-induced phosphorylation of ERK, JNK, p38, STAT3 and NF-κB (p65), suppresses the production of NO, IL-6, TNF-α and IL-1β, and also downregulates the levels of iNOS and COX-2. Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage.
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