2322293-84-3
Chemical Structure
(S)-PI3Kα-IN-4
- CAS No.: 2322293-84-3
- Formula:C25H23ClFN5O5S
- Molecular Weight:560.00
IUPAC Name: (S)-3-(6-(5-((2-chloro-4-fluorophenyl)sulfonamido)-6-methoxypyridin-3-yl)-4-oxoquinazolin-3(4H)-yl)-N,2-dimethylpropanamide
InChIKey: LPATWVFSBNDSHR-AWEZNQCLSA-N
SMILES: O=C(NC)[C@@H](C)CN1C=NC2=C(C=C(C3=CC(NS(=O)(C4=CC=C(F)C=C4Cl)=O)=C(OC)N=C3)C=C2)C1=O
Biological Activity: (S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-PI3Kα-IN-4 | 99.77% | (S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC50 of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer. | ||||||||||||||||||||
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Keywords
