2490309-83-4
2490309-83-4
Chemical Structure
HDAC-IN-41
- CAS. Nr.: 2490309-83-4
- Formula:C20H22N4O6S
- Molecular Weight:446.48
IUPAC Name: 4-((6-((2-aminophenyl)amino)-6-oxohexyl)oxy)-3-(phenylsulfonyl)-1,2,5-oxadiazole 2-oxide
InChIKey: OAEKUDSJACGENX-UHFFFAOYSA-N
SMILES: O=S(C1=[N+]([O-])ON=C1OCCCCCC(NC2=C(N)C=CC=C2)=O)(C3=CC=CC=C3)=O
Biological Activity: HDAC-IN-41 (Compound 7c) is a selective, orally active class I HDAC inhibitor with IC50 values of 0.62, 1.46 and 0.62 μM against HDAC1, HDAC2 and HDAC3, respectively. HDAC-IN-41 shows NO releasing activity[1].
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HDAC-IN-41 | HDAC-IN-41 (Compound 7c) is a selective, orally active class I HDAC inhibitor with IC50 values of 0.62, 1.46 and 0.62 μM against HDAC1, HDAC2 and HDAC3, respectively. HDAC-IN-41 shows NO releasing activity. | |||||||||||||||||||||
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