Cathepsin L-IN-7
Cathepsin L-IN-7 is an inhibitor of cathepsin L, cathepsin B and cathepsin S. Cathepsin L-IN-7 has an IC50 of 0.011 μM against cathepsin L and an IC50 of 0.062 μM against cathepsin S, while it shows weak inhibitory activity against cathepsin B. Cathepsin L-IN-7 binds to the active site of cysteine proteases and blocks their proteolytic function. Cathepsin L-IN-7 can be used in research on viral infections and cancer.
For research use only. We do not sell to patients.
- CAS No.: 1194047-02-3
- Formula: C27H33N5O6
- Molecular Weight:523.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Cathepsin Isoforms
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Biological Activity
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cathepsin L 0.011 μM (IC50) |
cathepsin S 0.062 μM (IC50) |
Cathepsin B 25 μM (IC50) |
Cathepsin L-IN-7 (Compound 93) (1 h) shows potent inhibitory activity against human Cathepsin L (IC50 = 0.011 μM) and Cathepsin S (IC50 = 0.062 μM), while exhibiting weak inhibition of Cathepsin B (IC50 = 25.000 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1194047-02-3
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Molecular Weight 523.58
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Formula C27H33N5O6
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SMILES
CCC(C=CC=C1)=C1NC(COC(NNC([C@@H](NC(OC(C)(C)C)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cathepsin L-IN-7 Related Classifications
HY-183940 Related Classifications
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