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Art. -Nr.: HY-107677

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A 844606

Name: A 844606
Brand: MedChemExpress
SKU: HY-107677
Price: 400.00 USD
Availability: InStock
Rating: 5 (1 reviews)

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease.

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CAS. Nr.: 861119-08-6
Formel: C₂₀H₂₀N₂O₂
Molecular Weight:320.39

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

A 844606 Chemical Structure

CAS. Nr.: 861119-08-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
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- Cellular Effect
Chemical Information
Reinheit & Dokumentation
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Biologische Aktivität

Beschreibung

A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
HEK293	EC₅₀	>100 μM Compound: 52	Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay	[PMID: 22281189]
Oocyte	EC₅₀	2.2 μM Compound: 52	Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay	[PMID: 22281189]

Chemical Information

CAS. Nr. 861119-08-6
Molecular Weight 320.39
Formel C₂₀H₂₀N₂O₂
SMILES

O=C1C2=C(OC3=CC=C(N4CC5CN(CC5C4)C)C=C31)C=CC=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Leung K. 2-(5-[11C]Methyl-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-xanthene-9-one. 2010 Oct 12 [updated 2011 Jan 19]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
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Biologische Aktivität

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Help & FAQs

Bioz

A 844606

Dihydro-β-erythroidine hydrobromide

PHA-543613

SEN12333

PNU-282987

AR-R17779 hydrochloride

Cotinine

Varenicline

A-582941 dihydrochloride

MG624

GTS-21 dihydrochloride

α-Bungarotoxin

Myosmine

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

A 844606 Related Classifications

HY-107677 Related Classifications

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