BAY-3827 (Standard)

BAY-3827 (Standard) is the analytical standard of BAY-3827 (HY-112083). This product is intended for research and analytical applications. BAY-3827, a chemical probe, is a potent and selective AMPK inhibitor with IC50 values of 1.4 nM at low (10 μM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 shows over 500-fold selectivity for most of the 331 Kinases. BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 and shows strongest anti-proliferative activity in androgen-dependent prostate cancer cell lines.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • CAS. Nr.: 2377576-35-5
  • Formel: C27H25FN6O
  • Molecular Weight:468.53
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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