FD2157
FD2157 is a photosensitive PI3K inhibitor, with IC50s of 43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ respectively. FD2157 potently inhibits cancer cell proliferation and induces cell apoptosis when exposed to 365 nm UV light.
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- CAS. Nr.: 3046403-79-3
- Formel: C27H21ClN6O8S
- Molecular Weight:625.01
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
43 nM, 83 nM, 84 nM, 14 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ[1]
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Cell Line
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Type | Value | Description | References |
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| B16 | IC50 |
8.8 μM
Compound: FD2157
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Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability incubated for 48 hrs irradiated with 365 nm uv light for 4 min by CCK-8 assay
Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability incubated for 48 hrs irradiated with 365 nm uv light for 4 min by CCK-8 assay
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[PMID: 37634762] |
Chemical Information
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CAS. Nr. 3046403-79-3
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Molecular Weight 625.01
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Formel C27H21ClN6O8S
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SMILES
O=C(OCC1=CC(OC)=C(OC)C=C1[N+]([O-])=O)N(N=C2)C(C2=C3)=NC=C3C4=CN=C(Cl)C(NS(=O)(C5=CC=CC=C5)=O)=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
FD2157 Related Classifications
HY-155996 Related Classifications
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