p53 Activator 5
Based on 1 Customer Validation
p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity. p53 Activator 5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- CAS. Nr.: 2636840-37-2
- Formel: C29H32F6N4O
- Molecular Weight:566.58
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Speicherung:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 2636840-37-2
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Appearance Solid
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Molecular Weight 566.58
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Formel C29H32F6N4O
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Color Brown to reddish brown
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SMILES
COC1=CC(C(F)(F)F)=CC=C1NCC#CC2=CC3=C(C=CC=C3N[C@@H](CC4)CC[C@H]4N(C)C)N2CC(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (176.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7650 mL | 8.8249 mL | 17.6498 mL | 44.1244 mL |
| 5 mM | 0.3530 mL | 1.7650 mL | 3.5300 mL | 8.8249 mL | |
| 10 mM | 0.1765 mL | 0.8825 mL | 1.7650 mL | 4.4124 mL | |
| 15 mM | 0.1177 mL | 0.5883 mL | 1.1767 mL | 2.9416 mL | |
| 20 mM | 0.0882 mL | 0.4412 mL | 0.8825 mL | 2.2062 mL | |
| 25 mM | 0.0706 mL | 0.3530 mL | 0.7060 mL | 1.7650 mL | |
| 30 mM | 0.0588 mL | 0.2942 mL | 0.5883 mL | 1.4708 mL | |
| 40 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1031 mL | |
| 50 mM | 0.0353 mL | 0.1765 mL | 0.3530 mL | 0.8825 mL | |
| 60 mM | 0.0294 mL | 0.1471 mL | 0.2942 mL | 0.7354 mL | |
| 80 mM | 0.0221 mL | 0.1103 mL | 0.2206 mL | 0.5516 mL | |
| 100 mM | 0.0176 mL | 0.0882 mL | 0.1765 mL | 0.4412 mL |
p53 Activator 5 Related Classifications
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