Vortioxetine hydrobromide (Standard)
Based on 1 Customer Validation
Vortioxetine (hydrobromide) (Standard) is the analytical standard of Vortioxetine (hydrobromide). This product is intended for research and analytical applications. Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.59%
- CAS. Nr.: 960203-27-4
- Formel: C18H23BrN2S
- Molecular Weight:379.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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HY-15414A
Vortioxetine hydrobromideSerotonin Transporter Inhibitor -
HY-15414
VortioxetineSerotonin Transporter Inhibitor -
HY-15414R
Vortioxetine (Standard)Serotonin Transporter Inhibitor -
HY-14262
VilazodoneSerotonin Reuptake Inhibitor -
HY-B0176A
Sertraline hydrochlorideSSRI -
HY-14261
Vilazodone HydrochlorideSER Inhibitor/5-HT1Areceptor Agonist -
HY-B0176AR
Sertraline hydrochloride (Standard)SSRI -
HY-42110
DeschloroclozapineMuscarinic-based DREADDs Agonist -
HY-B0161A
Duloxetine hydrochlorideSerotonin-norepinephrine Reuptake Inhibitor -
HY-B0103
FluvoxamineSerotonin Transporter Inhibitor -
HY-B0602
Desvenlafaxine5-HT/Norepinephrine Reuptake Inhibitor -
HY-14258A
Escitalopram oxalateSerotonin Reuptake Inhibitor
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 960203-27-4
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Appearance Solid
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Molecular Weight 379.36
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Formel C18H23BrN2S
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Color Light yellow to yellow
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SMILES
CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1.[H]Br
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Synonyms
Lu AA21004 hydrobromide (Standard)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Bang-Andersen B, et al. Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54(9):3206-21. [Content Brief]
[2]. Guilloux JP, et al. Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice. Neuropharmacology. 2013 May 28;73C:147-159. [Content Brief]
[3]. Theunissen EL, et al. A randomized trial on the acute and steady-state effects of a new antidepressant, vortioxetine (Lu AA21004), on actual driving and cognition. Clin Pharmacol Ther. 2013 Jun;93(6):493-501. [Content Brief]
[4]. Rothschild AJ, et al. Vortioxetine (Lu AA21004) 5mg in generalized anxiety disorder: results of an 8-week randomized, double-blind, placebo-controlled clinical trial in the United States. Eur Neuropsychopharmacol. 2012 Dec;22(12):858-66. [Content Brief]
[5]. Mork A, et al. Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder. J Pharmacol Exp Ther. 2012 Mar;340(3):666-75. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Vortioxetine hydrobromide (Standard) Related Classifications
HY-15414AR Related Classifications
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