Calythropsin
Calythropsin is a cytotoxic chalcone, with weak effect on mitosis, and presumably also on tubulin polymerization.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 152340-67-5
- Formule: C16H14O5
- Masse moléculaire:286.28
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Protocole
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
7 μM
Compound: 1
|
Cytotoxicity against mouse L1210 cells after 24 hrs
Cytotoxicity against mouse L1210 cells after 24 hrs
|
[PMID: 8277311] |
| RBL-1 | IC50 |
15 nM
Compound: 32
|
In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined
In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined
|
[PMID: 8254620] |
Chemical Information
-
CAS No. 152340-67-5
-
Masse moléculaire 286.28
-
Formule C16H14O5
-
SMILES
OC(C=C1/C=C/C(C2=C(C=C(C=C2)OC)O)=O)=C(C=C1)O
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
-
Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Calythropsin Related Classifications
HY-N11766 Related Classifications
Powered by Bioz