Methylolanthanin
Methylolanthanin (para-MLL) is a natural small-molecule metallophore identified in the culture supernatant of Methylobacterium extorquens AM1. Methylolanthanin binds lanthanide metal ions such as La3+, Nd3+ and Lu3+. It is applicable to studies related to lanthanide metabolism, bacterial metallophores, metal homeostasis and methylotrophic metabolism.
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- CAS No.: 3120945-90-3
- Formule: C40H58N6O11
- Masse moléculaire:798.92
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
In Vitro
Methylolanthanin (para-MLL) (10 μM; 15 min) forms insoluble complexes with La3+, Nd3+, Eu3+, and Lu3+ at pH 6.0, causing the complexes to precipitate from the solution[1].
Methylolanthanin (18.75 μM) exhibits low iron (III)-binding affinity and only weak ability to compete with the CAS/HDTMA complex for Fe3+ at pH 6.0[1].
Methylolanthanin forms the [MLL-H+Ln3+]2+ complex with La3+, Nd3+ and Lu3+[2].
Methylolanthanin (50 nM) significantly increases the growth yield of M. extorquens AM1 ΔmxaF and ΔmxaFΔmll mutants under conditions of 2 μM or 50 nM NdCl3[2].
Methylolanthanin binds Eu3+ within the micromolar and nanomolar concentration ranges and forms detectable Eu3+-MLL particles, with a log KSP of -12.07 for the precipitated complex[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3120945-90-3
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Masse moléculaire 798.92
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Formule C40H58N6O11
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SMILES
O=C(C(CC(NCCCCN(CCCCNC(C1=CC=C(C=C1)O)=O)C(C)=O)=O)(CC(NCCCCN(CCCCNC(C2=CC=C(C=C2)O)=O)C(C)=O)=O)O)O
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Synonyms
para-MLL
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)