Pomalidomide-cyclohexane-C-COOH
Pomalidomide-cyclohexane-C-COOH is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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- CAS No.: 2368941-28-8
- Formule: C20H21N3O6
- Masse moléculaire:399.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2368941-28-8
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Masse moléculaire 399.40
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Formule C20H21N3O6
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SMILES
O=C(O)CC1CCN(C=2C=CC=C3C(=O)N(C(=O)C32)C4C(=O)NC(=O)CC4)CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)