XAV-939 (Standard)
XAV-939 (Standard) is the analytical standard of XAV-939. This product is intended for research and analytical applications. XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98%
- CAS No.: 284028-89-3
- Formule: C14H11F3N2OS
- Masse moléculaire:312.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-15147
XAV-939Tankyrase Inhibitor -
HY-15147G
XAV-939 (GMP)Tankyrase Inhibitor -
HY-10162
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HY-10619
NiraparibPARP Inhibitor -
HY-10129
VeliparibPARP Inhibitor -
HY-10162R
Olaparib (Standard)PARP Inhibitor -
HY-16106
TalazoparibPARP Inhibitor -
HY-16910
WIKI4Tankyrase Inhibitor -
HY-W018800
4(3H)-QuinazolinoneAntibacterial agent -
HY-10619A
Niraparib hydrochloridePARP Inhibitor -
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JW 55PARP Inhibitor -
HY-10619B
Niraparib tosylatePARP Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 284028-89-3
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Masse moléculaire 312.31
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Formule C14H11F3N2OS
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SMILES
O=C1C(CSCC2)=C2N=C(C3=CC=C(C(F)(F)F)C=C3)N1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Mohit Narwal, et al. Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J Med Chem. 2013 Oct 24;56(20):7880-9. [Content Brief]
[2]. Nuha Almasoud, et al. Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells. Sci Rep. 2020 Oct 7;10(1):16746. [Content Brief]
[3]. Senxin Cai, et al. Mechanical stress reduces secreted frizzled-related protein expression and promotes temporomandibular joint osteoarthritis via Wnt/β-catenin signaling. Bone. 2022 Aug;161:116445. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
XAV-939 (Standard) Related Classifications
HY-15147R Related Classifications
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