CRBN ligand-870
CRBN ligand-870 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-870 can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 3026010-13-6
- Formula: C18H20N4O4
- Molecular Weight:356.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3026010-13-6
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Molecular Weight 356.38
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Formula C18H20N4O4
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SMILES
O=C1C=2C(=C3C(N4[C@](CO3)(CNCC4)[H])=CC2)CN1[C@@H]5C(=O)NC(=O)CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)