1. Cytokines
  2. Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)

Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)

Cat. No.: HY-P7003
Handling Instructions

Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

For research use only. We do not sell to patients.

Cytokines-MedChemExpress
Size Price Stock Quantity
10 μg $90 In-stock
Estimated Time of Arrival: December 31
50 μg $290 In-stock
Estimated Time of Arrival: December 31
100 μg $490 Get quote
250 μg   Get quote  

* Please select Quantity before adding items.

  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Species

Human

Source

CHO

Accession

Q9Y275

Gene ID

10673

Molecular Weight

Approximately 17 kDa

AA Sequence

AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL

Biological Activity
The ED50 is <20 ng/mL as measured by human RPMI 8226 cells, corresponding to a specific activity of >5.0 × 104 units/mg.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconstitution

Reconstitute the lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability

Lyophilized recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed) (rHuBAFF/TNFSF13B) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

B-cell activating factor (BAFF), a member of the tumor necrosis factor (TNF) superfamily, is secreted by various myeloid cells such as macrophages, dendritic cells, and neutrophils. BAFF is a potent survival factor for B cells and plays an essential role in peripheral B-cell homeostasis[1].

Documentation
References
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Product name:
Recombinant Human B cell Activating Factor/TNFSF13B (CHO-expressed)
Cat. No.:
HY-P7003
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