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Art. -Nr.: HY-P12259

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4F-P-4F peptide

4F-P-4F peptide is an apoA-I mimetic peptide with a class A amphipathic α-helical structure that acts on ABCA1 and SR-B. 4F-P-4F peptide induces cholesterol efflux from cholesterol-loaded mouse macrophages and promotes HDL remodeling in plasma. 4F-P-4F peptide can be used in research on asthma and atherosclerosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₂₉H₃₁₁N₄₇O₅₆
Molecular Weight:4618.20

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Kundenspezifische Peptidsynthese

4F-P-4F peptide Chemical Structure

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Preis

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

4F-P-4F peptide (1 h) mediates low levels of cholesterol efflux in human eosinophils^[1].
4F-P-4F peptide promotes cholesterol efflux from cholesterol-rich mouse macrophages^[2].
4F-P-4F peptide F promotes cholesterol efflux in ABCA1-transfected HeLa cells^[2].
4F-P-4F peptide (5 μM) significantly remodels human HDL^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 4618.20
Formel C₂₂₉H₃₁₁N₄₇O₅₆
Sequence

Asp-Trp-Phe-Lys-Ala-Phe-Tyr-Asp-Lys-Val-Ala-Glu-Lys-Phe-Lys-Glu-Ala-Phe-Pro-Asp-Trp-Phe-Lys-Ala-Phe-Tyr-Asp-Lys-Val-Ala-Glu-Lys-Phe-Lys-Glu-Ala-Phe
Sequence Shortening

DWFKAFYDKVAEKFKEAFPDWFKAFYDKVAEKFKEAF
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Rani A, et al. Peptide-based lipid nanodiscs suppress eosinophil recruitment and chemotaxis. Journal of controlled release : official journal of the Controlled Release Society. 2025 Sep 10;385:114060.

[2]. Leman LJ, et al. Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis. Journal of medicinal chemistry. 2014 Mar 27;57(6):2169-96.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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