DMG-PEG2000-COOH
DMG-PEG2000-COOH is a conjugate composed of DMG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DMG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
For research use only. We do not sell to patients.
- Purity : 97.37%
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
In Vitro
The structure of DMG-PEG-COOH comprises three key components that work synergistically:
DMG: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
COOH (carboxyl group): A reaction interface located at the end of the PEG chain, it can covalently link with molecules containing amino or hydroxyl groups (such as antibodies, peptides, and fluorescent dyes) through efficient chemical reactions such as amidation and esterification, achieving targeting or tracking functions.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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Appearance Solid
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Color White to off-white
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SMILES
O=C(CCCCCCCCCCCCC)OC(COC(CCCCCCCCCCCCC)=O)COCCOCC(O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DMG-PEG2000-COOH Related Classifications
HY-200288 Related Classifications
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