Diphenhydramine-d6 hydrochloride
Based on 1 Customer Validation
Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 1189986-72-8
- Formula: C17H16D6ClNO
- Molecular Weight:297.85
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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H1 Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1189986-72-8
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Unlabeled Cas 147-24-0
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Appearance Solid
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Molecular Weight 297.85
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Formula C17H16D6ClNO
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Color White to off-white
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SMILES
[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : 100 mg/mL (335.74 mM; Need ultrasonic)
DMSO : 83.33 mg/mL (279.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 3.3574 mL | 16.7870 mL | 33.5739 mL | 83.9349 mL |
| 5 mM | 0.6715 mL | 3.3574 mL | 6.7148 mL | 16.7870 mL | |
| 10 mM | 0.3357 mL | 1.6787 mL | 3.3574 mL | 8.3935 mL | |
| 15 mM | 0.2238 mL | 1.1191 mL | 2.2383 mL | 5.5957 mL | |
| 20 mM | 0.1679 mL | 0.8393 mL | 1.6787 mL | 4.1967 mL | |
| 25 mM | 0.1343 mL | 0.6715 mL | 1.3430 mL | 3.3574 mL | |
| 30 mM | 0.1119 mL | 0.5596 mL | 1.1191 mL | 2.7978 mL | |
| 40 mM | 0.0839 mL | 0.4197 mL | 0.8393 mL | 2.0984 mL | |
| 50 mM | 0.0671 mL | 0.3357 mL | 0.6715 mL | 1.6787 mL | |
| 60 mM | 0.0560 mL | 0.2798 mL | 0.5596 mL | 1.3989 mL | |
| 80 mM | 0.0420 mL | 0.2098 mL | 0.4197 mL | 1.0492 mL | |
| 100 mM | 0.0336 mL | 0.1679 mL | 0.3357 mL | 0.8393 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Diphenhydramine-d6 hydrochloride Related Classifications
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