147-24-0
147-24-0
Chemical Structure
Diphenhydramine hydrochloride
- CAS No.: 147-24-0
- Formula:C17H22ClNO
- Molecular Weight:291.82
IUPAC Name: 2-(benzhydryloxy)-N,N-dimethylethan-1-amine hydrochloride
InChIKey: PCHPORCSPXIHLZ-UHFFFAOYSA-N
SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Biological Activity: Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].
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Diphenhydramine hydrochloride | 99.93% | Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB). | ||||||||||||||||||||
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Diphenhydramine hydrochloride (Standard) | 99.90% | Diphenhydramine (hydrochloride) (Standard) is the analytical standard of Diphenhydramine (hydrochloride). This product is intended for research and analytical applications. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB). | ||||||||||||||||||||
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Diphenhydramine-d5 hydrochloride | 99.84% | Diphenhydramine-d5 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB). | ||||||||||||||||||||
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Diphenhydramine-d6 hydrochloride | 99.30% | Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-B0303RDiphenhydramine (Standard) -
Similarity Score 0.88
HY-W354470R2-(Benzhydryloxy)-N-methylethan-1-amine hydrochloride (Standard) -
Similarity Score 0.87
HY-B0303S1Diphenhydramine-d3 -
Similarity Score 0.86
HY-135740Diphenhydramine N-oxide -
Similarity Score 0.85
HY-135740SDiphenhydramine N-oxide-d6 -
Similarity Score 0.85
HY-B1126ROrphenadrine hydrochloride (Standard) -
Similarity Score 0.85
HY-138110RToladryl (Standard) -
Similarity Score 0.85
HY-B1568Bromodiphenhydramine -
Similarity Score 0.85
HY-B1568ABromodiphenhydramine hydrochloride -
Explore the MedChemAI to find more analogs
References
- [1]. Simons FE. H1-receptor antagonists. Comparative tolerability and safety. Drug Saf. 1994;10(5):350-380. [Content Brief]
- [2]. Sadiq MW, et al. Diphenhydramine active uptake at the blood-brain barrier and its interaction with oxycodone in vitro and in vivo. J Pharm Sci. 2011;100(9):3912-3923. [Content Brief]
