Diphenhydramine-d5 hydrochloride
Based on 1 Customer Validation
Diphenhydramine-d5 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 1219795-16-0
- Formula: C17H17D5ClNO
- Molecular Weight:296.85
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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H1 Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219795-16-0
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Unlabeled Cas 147-24-0
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Appearance Solid
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Molecular Weight 296.85
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Formula C17H17D5ClNO
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Color White to off-white
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SMILES
CN(C)CCOC(C1=CC=CC=C1)C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H].Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (336.87 mM; Need ultrasonic)
DMSO : 100 mg/mL (336.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.3687 mL | 16.8435 mL | 33.6870 mL | 84.2176 mL |
| 5 mM | 0.6737 mL | 3.3687 mL | 6.7374 mL | 16.8435 mL | |
| 10 mM | 0.3369 mL | 1.6844 mL | 3.3687 mL | 8.4218 mL | |
| 15 mM | 0.2246 mL | 1.1229 mL | 2.2458 mL | 5.6145 mL | |
| 20 mM | 0.1684 mL | 0.8422 mL | 1.6844 mL | 4.2109 mL | |
| 25 mM | 0.1347 mL | 0.6737 mL | 1.3475 mL | 3.3687 mL | |
| 30 mM | 0.1123 mL | 0.5615 mL | 1.1229 mL | 2.8073 mL | |
| 40 mM | 0.0842 mL | 0.4211 mL | 0.8422 mL | 2.1054 mL | |
| 50 mM | 0.0674 mL | 0.3369 mL | 0.6737 mL | 1.6844 mL | |
| 60 mM | 0.0561 mL | 0.2807 mL | 0.5615 mL | 1.4036 mL | |
| 80 mM | 0.0421 mL | 0.2105 mL | 0.4211 mL | 1.0527 mL | |
| 100 mM | 0.0337 mL | 0.1684 mL | 0.3369 mL | 0.8422 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Diphenhydramine-d5 hydrochloride Related Classifications
HY-B0303AS1 Related Classifications
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